When you compare a spit test to the current way of how throat level reflux (LPR) is determined via barium swallow , upper endoscopy (EGD), and 24 hour ph/impedance testing , it sounds quite attractive. How does such a test work? It basically looks for a stomach protein called pepsin. Given reflux is when stomach contents moves up towards the mouth and pepsin is a protein ONLY produced in the stomach... pepsin should NOT be found in the throat/mouth. As such, the test can state &qu…