Though one should always use an EpiPen that is not expired, it is better to use an expired EpiPen to treat anaphylaxis than to do nothing at all. A few studies published between 2000 and 2017 suggest that epipens have a shelf-life much longer than the printed expiration date. A study published in May 2017 as well as two earlier studies published in April 2015 and May 2000 suggest that even if the epipen is expired, it is still effective and safe for use in severe allergic reactions …