Researchers have discovered that there is a very small, but significant association between birth defects and use of nasal decongestants in the first trimester of pregnancy. Unfortunately, decongestants (ie sudafed, afrin, etc) are also one of the most popular medications purchased over-the-counter to treat symptoms of nasal congestion , runny nose, and allergies . In particular, three strong associations were found: • Phenylephrine and endocardial cushion defects • Phenylpropanolam…